The role of porcine reproductive and respiratory syndrome virus infection in immune phenotype and Th1/Th2 balance of dendritic cells
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- 作者：Jinling Liua ; Shu Weib ; 1 ; Lixia Liua ; 1 ; Fengping Shanc ; Yujun Zhaoa ; Guoshun Shena ; Shenguoshun@sohu.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：PRRSV ; Dendritic cell ; Immunophenotype ; Thl /Th2
- 刊名：Developmental & Comparative Immunology
- 出版年：2016
- 出版时间：December 2016
- 年：2016
- 卷：65
- 期：Complete
- 页码：245-252
- 全文大小：1764 K
文摘
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PRRSV LN strain infection could impair the normal antigen presentation ability of Mo-DCs of porcine peripheral blood.
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PRRSV LN strain infection could influence the mature of Mo-DCs by down-regulating the expressions of costimulatory molecules.
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PRRSV LN could lead to inadequate in the adaptive immune response in early PRRSV infection by causing the Thl/Th2 unbalance.