Metabolomics can rapidly assess the collective small molecule content in biofluids.
Previous studies focused on urine of wild type mice and now extending to radiosensitive mice.
The Parp1−/− mice were utilized as a model radiosensitive mouse line.
Time-dependent perturbations are evident in different metabolic pathways.
Metabolomics can be used to dissect the effects of genotoxic agents on metabolism.