Metabolic targets of endocrine disrupting chemicals assessed by cord blood transcriptome profiling
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- 作者：Sylvie Remya ; b ; sylvie.remy@uantwerpen.be" class="auth_mail" title="E-mail the corresponding author ; Eva Govartsb ; Britt Wensb ; Patrick De Boeverb ; c ; Elly Den Hondb ; d ; Kim Croese ; Isabelle Sioenf ; g ; Willy Baeyense ; Nicolas van Larebekee ; h ; Janna Koppei ; Adrian Covacij ; Thomas Schettgenk ; Vera Nelenl ; Juliette Leglerm ; Greet Schoetersb ; n ; o
- 关键词：DDT ; dichlorodiphenyltrichloroethane ; EDC ; endocrine disrupting chemicals ; FLEHS(I/II/III) ; Flemish Environment and Health Survey (I/II/III) ; HNF1A ; hepatocyte nuclear factor 1 homeobox A ; HPA ; hypothalamic-pituitary-adrenal ; ICA1 ; islet cell autoantigen 1 ; IL ; interleukin ; IPA ; ingenuity pathway analysis (Ingenuity Systemsâ ; ) ; IQR ; interquartile range ; IRS2 ; insulin receptor substrate ; NR3C1 ; glucocorticoid receptor ; OBELIX ; FP7 project ; obesogenic Endocrine disrupting chemicals linking pre
- 刊名：Reproductive Toxicology
- 出版年：2016
- 出版时间：October 2016
- 年：2016
- 卷：65
- 期：Complete
- 页码：307-320
- 全文大小：1569 K
文摘
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New approach to identify influential variables in OMICS wide epidemiologic analysis.
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Cord blood transcriptome reveals early targets of endocrine disrupting chemicals.
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Results suggest a role for the glucocorticoid receptor.