Temporal dynamics of ‘HoBi’-like pestivirus quasispecies in persistently infected calves generated under experimental conditions

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• 作者：Matheus N. Weber^a ; Fernando V. Bauermann^b ; Clá ; udio W. Canal^a ; Darrell O. Bayles^b ; John D. Neill^b ; Julia F. Ridpath^b ; ^{julia.ridpath@ars.usda.gov}
• 关键词：Pestivirus ; Persistent infection ; Quasispecies ; &lsquo ; HoBi&rsquo ; -like
• 刊名：Virus Research
• 出版年：2017
• 出版时间：2 January 2017
• 年：2017
• 卷：227
• 期：Complete
• 页码：23-33
• 全文大小：2450 K
• 卷排序：227

文摘

Quasispecies composition in ‘HoBi’-like PI animals compared temporally. Genetic variability in viral mutant clouds increased along time. Absence of a putative N-glycosylation site represented an advantage in viral variants. Variations in viral swarm occurred over time and were dependent on host factor.