Role of computed tomography on large B-cell non-Hodgkin’s lymphoma follow-up and the risk of radiation-induced neoplasm: A retrospective cohort study
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- 作者：Lucí ; a Grañ ; aa ; lu_rx@hotmail.com" class="auth_mail" title="E-mail the corresponding author ; Alfonso Calzadob ; calzado@med.ucm.es" class="auth_mail" title="E-mail the corresponding author ; Paula Herná ; ndeza ; phmaula@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Ricardo Rodrí ; gueza ; rrodriguez.hcsc@salud.madrid.org" class="auth_mail" title="E-mail the corresponding author
- 关键词：CT ; computed tomography ; LAR ; life attributable risk ; BEIR ; Biological Effects of Ionizing Radiation ; DLBCL ; diffuse large B-cell non-Hodgkin&rsquo ; s lymphoma ; R-CHOP ; rituximab ; cyclophosphamide ; doxorubicin ; vincristine ; and prednisone ; PACS ; picture archiving and communication system ; ICRP ; International Commission on Radiological Protection ; CTDIvol ; volumetric CT dose index ; DLP ; dose-length product ; SSDE ; size-specific dose estimate ; AAPM ; American Association of Physicists in Medicine ; ER
- 刊名：European Journal of Radiology
- 出版年：2016
- 出版时间：March 2016
- 年：2016
- 卷：85
- 期：3
- 页码：673-679
- 全文大小：409 K
文摘
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The optimal strategy for relapse detection after curative treatment of large-cell B lymphoma is still controversial.
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Our findings suggest that the relapse is most commonly suspected by the patient or the clinician and it is rarely detected only by imaging.
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The risk of surveillance are not fully justified as it probably implies exposure to unnecessary radiation, which has been linked to cancer development.
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59% of our patients had cumulative effective dose greater than 100 mSv due to surveillance CT, the threshold often considered for significant risk.