Re-evaluation of the Blood-Brain Barrier in the Presence of Alzheimer’s Disease Pathology

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• 作者：Jason D. Ulrich¹ ; ² ; ³ ; Tien-Phat Huynh¹ ; ² ; ³ ; David M. Holtzman¹ ; ² ; ³ ; ^{holtzman@neuro.wustl.edu" class="auth_mail" title="E-mail the corresponding author}
• 刊名：Neuron
• 出版年：2015
• 出版时间：21 October 2015
• 年：2015
• 卷：88
• 期：2
• 页码：237-239
• 全文大小：1218 K

文摘

Blood-brain barrier disruption is believed to occur in Alzheimer’s disease, which could influence the bioavailability of drugs within the brain. However, in this issue of Neuron, Bien-Ly et al. (2015) report no evidence of widespread blood-brain barrier dysfunction.