Dendritic cells in brain diseases
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- 作者：Peter Ludewiga ; Mattia Galliziolib ; Xabier Urrac ; d ; Sarah Behra ; Vanessa H. Braitd ; Mathias Gelderbloma ; Tim Magnusa ; Anna M. Planasb ; d ; anna.planas@iibb.csic.es" class="auth_mail" title="E-mail the corresponding author
- 关键词：Aβ ; amyloid-β ; ABRA ; amyloid-β-related angiitis ; AD ; Alzheimer's disease ; APC ; antigen presenting cell ; APP ; amyloid precursor protein ; Arg-1 ; arginase-1 ; B7-H1 ; human B7 homolog 1 (PD-L1) ; Batf3 ; basic leucine zipper transcriptional factor ATF-like 3 ; BBB ; blood&ndash ; brain barrier ; BDCA ; blood dendritic cell antigen ; BDCA-1 ; CD1c ; BDCA-2 ; CD303 ; BDCA-3 ; CD141 ; thrombomodulin ; BDCA-4 ; CD304 ; Neuropilin-1 ; BMDC ; bone marrow-derived DC ; C1q ; 1st C1 complex subcomponent of classical complement act
- 刊名：Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
- 出版年：2016
- 出版时间：March 2016
- 年：2016
- 卷：1862
- 期：3
- 页码：352-367
- 全文大小：1059 K
文摘
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Neuroinflammation induces the presence DC-like cells in the brain.
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10">DCs orchestrate innate and adaptive immune responses in brain diseases.
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15">DC responses are complex and disease-dependent.
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Modulation of DC responses and DC-based therapies are under investigation