Signaling via the CytoR/JAK/STAT/SOCS pathway: Emergence during evolution
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- 作者：Clifford Lionguea ; b ; Tarannum Taznina ; Alister C. Warda ; b ; award@deakin.edu.au" class="auth_mail" title="E-mail the corresponding author ; alister.ward@deakin.edu.au" class="auth_mail" title="E-mail the corresponding author
- 关键词：CHD ; cytokine receptor homology domain ; CytoR ; cytokine receptor ; EST ; expressed sequence tag ; FBN ; fibronectin ; FERM ; four-point-one ; ezrin ; radixin ; moesin ; HP ; heterochromatin protein ; Ig ; immunoglobulin ; JAK ; Janus kinase ; SH2 ; Src-homology 2 ; SOCS ; suppressor of cytokine signalling ; STAT ; signal transducer and activator of transcription ; WGS ; whole genome sequence
- 刊名：Molecular Immunology
- 出版年：2016
- 出版时间：March 2016
- 年：2016
- 卷：71
- 期：Complete
- 页码：166-175
- 全文大小：2457 K
文摘
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CytoR/JAK/STAT/SOCS components arose independently over a large time frame.
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Complete pathway coalesced in bilateria.
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CytoR/JAK/STAT assembly consistent with retrograde model of pathway evolution.