Effect of paradoxical sleep deprivation and stress on passive avoidance behavior

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• 作者：Hong Wang ; Jian ; van den Buuse ; Maarten ; Wen Tian ; Shao ; Ye Ma ; Yuan
• 关键词：Paradoxical sleep ; Step-through ; Passive avoidance ; Aversive memory
• 刊名：Physiology and Behavior
• 出版年：2003
• 出版时间：September, 2003
• 年：2003
• 卷：79
• 期：4-5
• 页码：591-596
• 全文大小：226 K

文摘

Previous studies have shown that several types of stress can induce memory impairment. However, the memory effects of paradoxical sleep deprivation (PSD), a stressor in itself, are unclear. We therefore compared passive avoidance behavior of rats undergoing PSD and PSD stress yoked-control (PSC) using the “reversed flowerpot method.” When rats were kept isolated on a PSC platform for 24 h immediately after criterion training, retention trials showed impaired aversive memory storage. When delayed for 24 h after criterion training, PSC stress did not disrupt retention performance. In rats subjected to PSD, either immediately or 24 h after criterion training, there was no disruption of aversive memory consolidation. These results suggest that, during stress, paradoxical sleep plays a role in erasing aversive memory traces, in line with the theory that we “dream in order to forget.”