The sperm quality and clinical outcomes were not affected by sY152 deletion in Y chromosome for oligozoospermia or azoospermia men after ICSI treatment
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- 作者：Yuanchang Zhu1 ; Tonghua Wu1 ; Guangui Li ; Biao Yin ; Hongjie Liu ; Caiyun Wan ; Hongzhan Zhang ; Yong Zeng ; zengyong1966@gmail.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：AZF ; azoospermia factor ; ICSI ; intracytoplasmic sperm injection ; SCOS ; sertoli cell only syndrome ; STS ; sequence tagged site ; EAA ; European Academy of Andrology ; EMGQ ; European Molecular Genetics Quality ; CASA ; computer assisted semen analysis ; TESE ; testicular sperm extraction ; SAGE ; serum protein substitute ; PAR ; pseudoautosomal region
- 刊名：Gene
- 出版年：2015
- 出版时间：1 December 2015
- 年：2015
- 卷：573
- 期：2
- 页码：233-238
- 全文大小：357 K
文摘
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sY152 is the most common deletion marker in the AZFc region.
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Single sY152 deletion can cause severe oligozoospermia or azoospermia.
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Single sY152 deletion might cause a lower fertilization rate.
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No adverse effects on sperm quality and clinical outcomes were found.
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The study may provide more information for consultation in AZF deletion patients.