Expression differences of miRNAs and genes on NF-魏B pathway between the healthy and the mastitis Chinese Holstein cows
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- 作者：Ling Chen ; Xiaolin Liu ; liuxiaolin@nwsuaf.edu.cn" class="auth_mail ; Zhixiong Li ; Hongliang Wang ; Yu Liu ; Hua He ; Jing Yang ; Fubiao Niu ; Lijun Wang ; Jiazhong Guo
- 关键词：NF-魏B ; nuclear factor kappa B ; I魏B ; inhibitor of NF-魏B ; IKK ; inhibitor of NF-魏B kinase ; RHD ; rel homology domain ; NLS ; nuclear localization signal ; qRT-PCR ; quantitative real-time PCR ; TRAF6 ; TNF receptor-associated factor 6 ; IRAK1 ; interleukin receptor associated kinase ; STAT3 ; signal transducer and activator of transcription 3 ; NKRF ; NF-魏B repressing factor ; CYLD ; cylindrical tumor gene ; NRE ; negative regulatory elements ; IL-8 ; interleukin 8 ; IFN尾 ; interferon尾
- 刊名：Gene
- 出版年：15 July 2014
- 年：2014
- 卷：545
- 期：1
- 页码：117-125
- 全文大小：671 K
文摘
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Variation of miRNAs and genes on NF-魏B pathway between healthy and mastitis cows.
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The total miRNAs decline and most of the genes expression rise in mastitis cows.
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NF-魏B pathway is active in mastitis as a result of the decrease of miRNAs.
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NF-魏B pathway is inactive as the miRNAs enhancing inhibition in healthy cows.
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Some miRNAs could be used as new markers for the dairy mastitis prognosing.