Activation of dopamine D4 receptors within the anterior cingulate cortex enhances the erroneous expectation of reward on a rat slot machine task
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- 作者：P.J. Cocker ; 1 ; pcocker@psych.ubc.ca" class="auth_mail" title="E-mail the corresponding author ; J.G. Hosking ; W.S. Murch ; L. Clark ; C.A. Winstanley ; 1 ; cwinstanley@psych.ubc.ca" class="auth_mail" title="E-mail the corresponding author
- 关键词：Gambling ; Near-miss ; Anterior cingulate cortex ; Dopamine ; D4
- 刊名：Neuropharmacology
- 出版年：2016
- 出版时间：June 2016
- 年：2016
- 卷：105
- 期：Complete
- 页码：186-195
- 全文大小：1203 K
文摘
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On a rodent slot machine, rats share key behavioural features with human gamblers.
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Provides insight into cognitive biases that may contribute to gambling disorder.
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The anterior cingulate cortex is critically involved in differentiating wins/losses.
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D4 receptors within the anterior cingulate mediate attributions of salience.