A retrospective clinical investigation.
An academic medical center.
One hundred twenty-five Marfan patients who had undergone aortic surgery.
None.
The indications for aortic surgery were aortic aneurysm and/or dissection in the 125 Marfan patients. The most commonly performed procedure was the Bentall in 92 patients. Sixteen patients underwent total arch replacement combined with stented elephant trunk implantation. Ten patients underwent the David procedure. Overall in-hospital and 30-day mortality rate was 1.6 % . The survival rate was 97.5 % , 91.4 % , and 74.2 % at 1, 5, and 10 years after surgery, respectively. The reoperation rate was 2.5 % , 12.9 % , and 32.9 % at 1, 5, and 10 years after surgery, respectively. Multivariate analysis revealed that increased systolic blood pressure (Sys BP) was the predictor of death (p < 0.05), and body mass index and smoking were significant predictors of reoperation (p < 0.05).
The present findings report the factors influencing the prognosis of Chinese patients with MFS after aortic surgical procedures. Managing these risk factors may enable health care professionals to improve the prognosis of MFS patients after aortic surgical procedures.