Experimental evidences for hsa-miR-497-5p as a negative regulator of SMAD3 gene expression
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- 作者：Meisam Jafarzadeha ; 1 ; Bahram M. Soltania ; soltanib@modares.ac.ir" class="auth_mail" title="E-mail the corresponding author ; Sadat Dokanehiifarda ; 1 ; Maryam Kaya ; Nasser Aghdamib ; Saman Hosseinkhanic
- 关键词：TGF-β ; transforming growth factor β ; TRE ; TPA responsive element ; CDC ; cardiosphere-derived cells ; MREs ; miRNA recognition elements ; RISC ; RNA-induced silencing complex
- 刊名：Gene
- 出版年：2016
- 出版时间：25 July 2016
- 年：2016
- 卷：586
- 期：2
- 页码：216-221
- 全文大小：588 K
文摘
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Hsa-miR-497-5p has inhibited cell cycle progression in G0/G1 phase.
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Hsa-miR-497-5p directly interact with 3′-UTR sequences of SMAD3 transcript.
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Hsa-miR-497-5p is potentially one of the regulators of the TGFβ signaling pathway.