Characterization and identification of isoflavonoid glycosides in the root of Spiny restharrow (Ononis spinosa L.) by HPLC-QTOF-MS, HPLC-MS/MS and NMR
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- 作者：Nó ; ra Gampea ; Andrá ; s Darcsia ; Szilvia Lohnerb ; Szabolcs Bé ; nia ; beni.szabolcs@pharma.semmelweis-univ.hu" class="auth_mail" title="E-mail the corresponding author ; Lá ; szló ; Kursinszkia ; kursinszki.laszlo@pharma.semmelweis-univ.hu" class="auth_mail" title="E-mail the corresponding author
- 关键词：Isoflavone ; Pterocarpan ; Dihydroisoflavone ; Structural analysis ; MS fragmentation pattern
- 刊名：Journal of Pharmaceutical and Biomedical Analysis
- 出版年：2016
- 出版时间：10 May 2016
- 年：2016
- 卷：123
- 期：Complete
- 页码：74-81
- 全文大小：1156 K
文摘
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HPLC–MS/MS and HPLC-QTOF-MS methods were developed to investigate isoflavonoids.
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Structural characterization was based on aglycone fragmentation and NMR experiments.
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Three novel isoflavonoids and their derivatives were found in restharrow root.
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Fragmentation pathways for sativanone and onogenin are presented.
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34 isoflavonoid derivatives were identified.