Effect of organochlorine pesticides exposure on the maize root metabolome assessed using high-resolution magic-angle spinning 1H NMR spectroscopy
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- 作者：Claire Blondela ; b ; Farid Khelalfaa ; b ; Sté ; phane Reynauda ; b ; Florence Fauvellec ; Muriel Ravetona ; b ; muriel.raveton@ujf-grenoble.fr" class="auth_mail" title="E-mail the corresponding author
- 关键词：Metabolomic ; Transcriptomic ; Maize ; Roots ; Organochlorines
- 刊名：Environmental Pollution
- 出版年：2016
- 出版时间：July 2016
- 年：2016
- 卷：214
- 期：Complete
- 页码：539-548
- 全文大小：2305 K
文摘
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Maize root response to organochlorine exposure was examined using 1H-HRMAS NMR method.
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Root metabolome showed significant OCP disturbances and dose-dependent fluctuations.
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OCP exposures altered the balance between glycolysis/gluconeogenesis.
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OCPs disturbed trans-aconitate, succinate, fumarate, acetate and fatty acid contents.
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OCPs increased protein/lipid catabolism (asparagine & oxidized fatty acid markers).