Beneficial effects of home-based cardiac rehabilitation on metabolic profiles in coronary heart-disease patients

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• 作者：Jing-Ting Chen^a ; Tsung-Hsien Lin^b ; ^c ; Wen-Chol Voon^b ; ^c ; Wen-Ter Lai^b ; ^c ; Mao-Hsiung Huang^a ; ^c ; Sheng-Hsiung Sheu^b ; ^c ; Chun-Kai Chen^d ; ^e ; ^{1000421@cc.kmuh.org.tw" class="auth_mail" title="E-mail the corresponding author}
• 关键词：Cardiac rehabilitation ; Coronary heart disease ; Exercise capacity ; Metabolic syndrome
• 刊名：The Kaohsiung Journal of Medical Sciences
• 出版年：2016
• 出版时间：May 2016
• 年：2016
• 卷：32
• 期：5
• 页码：267-275
• 全文大小：346 K

文摘

Coronary heart disease (CHD) is a major cause of morbidity and mortality in developed countries. Metabolic syndrome (MetS) is associated with increased risk of CHD. Cardiac rehabilitation is considered an effective intervention and a Class I indication in patients with CHD. This study was designed to evaluate the effects of home-based, integrated cardiac rehabilitation (HBICR) of patients with CHD in modifiable risk-factor control and exercise capacity. Sixty-four patients with CHD were investigated and randomized into intervention and control groups. The intervention group received a HBICR containing medication use, exercise program, smoking-cessation counseling, and education regarding risk factors, nutrition, and the necessity of continuing the program, whereas the control group received traditional care. Baseline and follow-up assessments at 3 months and 12 months, including body composition, metabolic syndrome risk score, and biochemical tests were performed in all patients. Additionally, cardiopulmonary function tests were also performed at baseline and 3-month follow-up assessments. There was a significant between-group, within-group, and interaction effect found in the MetS Z scores. Significant within-group effects were also observed in modified Adult Treatment Panel III score, waist circumference, high-density lipoprotein, and low-density lipoprotein. However, several cardiopulmonary parameters did not differ significantly at 3-month follow-up between the two groups, including peak V̇O₂, peak heart rate, peak respiratory exchange ratio, anaerobic threshold V̇O₂, heart-rate reserve, and heart-rate recovery after 1 min and after 2 min. Our results showed that HBICR exhibited significant positive effects on modifiable risk-factor control in CHD patients.