Implication of genomic characterization in synchronous endometrial and ovarian cancers of endometrioid histology
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- 作者：Angel Chaoa ; 1 ; Ren-Chin Wub ; 1 ; Shih-Ming Jungb ; 1 ; Yun-Shien Leec ; d ; Shu-Jen Chene ; Yen-Lung Lue ; Chia-Lung Tsaic ; Chiao-Yun Lina ; Yun-Hsin Tanga ; Ming-Yu Chena ; Huei-Jean Huanga ; Hung-Hsueh Choua ; Kuan-Gen Huanga ; Ting-Chang Changa ; Tzu-Hao Wanga ; c ; knoxtn@cgmh.org.tw" class="auth_mail" title="E-mail the corresponding author ; Chyong-Huey Laia ; sh46erry@ms.hinet.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：Endometrial cancer ; Ovarian cancer ; Synchronous ; Massively parallel sequencing (MPS) ; Copy number alteration
- 刊名：Gynecologic Oncology
- 出版年：2016
- 出版时间：October 2016
- 年：2016
- 卷：143
- 期：1
- 页码：60-67
- 全文大小：1474 K
文摘
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The majority of SEOCs with endometrioid histology were single primary tumors with metastatic disease.
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Clinicopathological criteria used to determine SEOCs must be adjusted.
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Testing of copy number alterations on SEOCs may help determining the need of adjuvant therapy.