The GRIM-19 plays a vital role in shrimps' responses to Vibrio alginolyticus
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- 作者：Ting Peng1 ; Mei-mei Gu1 ; Chang-sheng Zhao ; Wei-na Wang ; wangwn@scnu.edu.cn" class="auth_mail" title="E-mail the corresponding author ; weina63@aliyun.com" class="auth_mail" title="E-mail the corresponding author ; Ming-zhu Huang ; Chen-ying Xie ; Yu-chao Xiao ; Gui-Hong Cha ; Yuan Liu
- 关键词：Litopenaeus vannamei ; GRIM-19 ; JAK/STAT pathway ; dsRNA interfering technique
- 刊名：Fish & Shellfish Immunology
- 出版年：2016
- 出版时间：February 2016
- 年：2016
- 卷：49
- 期：Complete
- 页码：34-44
- 全文大小：1073 K
文摘
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The LvGrim-19 gene was cloned from Litopenaeus vannamei and characterized.
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The significant decreases in respiratory burst and apoptosis in those LvGrim-19 silenced shrimp compared to the controls.
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LvGrim-19 regulates STAT and JAK expression level.
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LvGrim-19 play a key role in L. vannamei resistance against Vibrio alginolyticus.