Berberine in combination with yohimbine attenuates sepsis-induced neutrophil tissue infiltration and multiorgan dysfunction partly via IL-10-mediated inhibition of CCR2 expression in neutrophils
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- 作者：Yuan Wang1 ; Faqiang Wang1 ; Duomeng Yang ; Xiangxu Tang ; Hongmei Li ; Xiuxiu Lv ; Daxiang Lu ; Huadong Wang ; owanghd@jnu.edu.cn" class="auth_mail" title="E-mail the corresponding author
- 关键词：Berberine ; Yohimbine ; Sepsis ; IL-10 ; Chemokine receptor CCR2
- 刊名：International Immunopharmacology
- 出版年：2016
- 出版时间：June 2016
- 年：2016
- 卷：35
- 期：Complete
- 页码：217-225
- 全文大小：1234 K
文摘
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Berberine and yohimbine therapy up-regulates IL-10 expression in septic mice.
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Berberine and yohimbine reduce CLP-induced neutrophil tissue infiltration via IL-10.
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Berberine and yohimbine attenuate CLP-induced multiple organ damage via IL-10.
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Berberine and yohimbine inhibit CLP-induced CCR2 expression in neutrophils via IL-10.