Co-delivery of antineoplastic and protein drugs by chitosan nanocapsules for a collaborative tumor treatment

详细信息    查看全文

• 作者：Dong-Yan Wu^a ; ¹ ; Yu Ma^a ; ¹ ; Xiao-Shuang Hou^a ; Wen-Jie Zhang^a ; ^b ; Pei Wang^a ; ^b ; Huan Chen^c ; Bo Li^a ; Can Zhang^b ; Ya Ding^a ; ^{ayanju@163.com}
• 关键词：Chitosan ; Amino acid derivatives ; Nanocapsules ; Co-delivery ; Caspase-3
• 刊名：Carbohydrate Polymers
• 出版年：2017
• 出版时间：10 February 2017
• 年：2017
• 卷：157
• 期：Complete
• 页码：1470-1478
• 全文大小：3271 K
• 卷排序：157

文摘

Nanocapsules were prepared by amino acid derivatives of chitosan. A simple and quick emulsification method to prepare nanocapsules. A general co-delivery system for chemical drug and protein. Enhanced tumor cell inhibition and apoptosis in HeLa cells.