Post-traumatic stress disorder after typhoon disaster and its correlation with platelet 5-HT concentrations

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• 作者：Jun-Cheng Guo¹ ; ² ; Zhi-Liang Tian³ ; Xiao-Dan Wang⁴ ; Min Guo¹ ; ^{g2002m@163.com" class="auth_mail" title="E-mail the corresponding author} ; Meng-Yong-Wei Li¹ ; Yun-Suo Gao¹ ; Xiang-Ling Jiang¹ ; Lin-Mei Fu¹ ; Tao Huang⁴ ; Xiang Li¹ ; Shu-Feng Yu¹ ; Li You¹
• 关键词：Post-traumatic stress disorder ; Influential factors ; 5-HT ; Typhoon
• 刊名：Asian Pacific Journal of Tropical Medicine
• 出版年：2016
• 出版时间：September 2016
• 年：2016
• 卷：9
• 期：9
• 页码：913-915
• 全文大小：248 K

文摘

To investigate residents' psychological stress factors and research the correlation between post-traumatic stress disorder (PTSD) and platelet 5-HT concentrations so as to provide scientific bases for diagnosis and treatment of PTSD and psychological intervention for people in the disaster area.

Methods

A questionnaire survey of 5 500 residents who have accepted psychological help was conducted by the emphatic investigation method. While high performance liquid chromatography was used to detect the platelet serotonin concentration of 100 PTSD patients and 100 healthy people.

Results

(1) Of the 5 114 cases, 3 167 (61.93%) showed positive results in screening for psychological stress symptoms, and 399 (7.8%) were tested having apparent PTSD symptoms. Male and female prevalence showed no significant difference (χ² = −0.380, P = 0.704). The differences of prevalence between different age groups were statistically significant (χ² = 381.89, P = 0.000). (2) The differences in the level of platelet 5-HT between PTSD patients and normal control group were statistically significant.

Conclusions

The typhoon of Hainan Province caused relatively large psychological problems to the disaster victims. Compared with normal control group, the platelet 5-HT levels of PTSD patients in the disaster areas are lower. It may be related to incidents exposure levels, cultural background, religious ideas, social concerns and psychological rescue of the residents who live in the disaster areas of Hainan.