In-situ itraconazole treatment improves survival rate during an amphibian chytridiomycosis epidemic
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- 作者：Michael A. Hudsona ; b ; c ; Michael.Hudson@ioz.ac.uk" class="auth_mail" title="E-mail the corresponding author ; Richard P. Youngc ; d ; Javier Lopeze ; Lloyd Martinf ; Calvin Fentonf ; Rachel McCreag ; Richard A. Griffithsb ; Sarah-Louise Adamsc ; Gerard Grayf ; Gerardo Garciae ; Andrew A. Cunninghama
- 关键词：Bd ; Batrachochytrium dendrobatidis ; CJS ; Cormack&ndash ; Jolly&ndash ; Seber ; CMR ; capture&ndash ; mark&ndash ; recapture ; DNA ; deoxyribonucleic acid ; GE ; genome equivalent ; IT ; itraconazole treatment ; NBC ; non-bath control ; PCR ; polymerase chain reaction ; PIT ; passive integrated transponder ; SWC ; stream water control
- 刊名：Biological Conservation
- 出版年：2016
- 出版时间：March 2016
- 年：2016
- 卷：195
- 期：Complete
- 页码：37-45
- 全文大小：786 K
文摘
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We test in-situ antifungal treatment for amphibian chytridiomycosis in the field.
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Treatment increased survival and loss of infection compared to untreated frogs.
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On the cessation of itraconazole treatment all benefits were lost.
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Models predict treatment increases time to population extinction by 60%.
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In-situ antifungal treatment could be a useful short term mitigation measure.