BDNF promotes the growth of human neurons through crosstalk with the Wnt/β-catenin signaling pathway via GSK-3β
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- 作者：Jin-wei Yanga ; b ; 1 ; yangjinwei800908@163.com" class="auth_mail" title="E-mail the corresponding author ; Jin Rua ; b ; 1 ; rujin227@163.com" class="auth_mail" title="E-mail the corresponding author ; Wei Maa ; mawei343897745@163.com" class="auth_mail" title="E-mail the corresponding author ; Yan Gaoa ; c ; flystaryanzi@163.com" class="auth_mail" title="E-mail the corresponding author ; Zhang Lianga ; ynkml-z@163.com" class="auth_mail" title="E-mail the corresponding author ; Jia Liub ; 791489440@qq.com" class="auth_mail" title="E-mail the corresponding author ; Jian-hui Guob ; guojianhuikm@163.com" class="auth_mail" title="E-mail the corresponding author ; Li-yan Lia ; kmliyanl@163.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：BDNF ; Wnt/β-catenin signaling ; Human neuron ; BIO ; GSK-3β
- 刊名：Neuropeptides
- 出版年：2015
- 出版时间：December 2015
- 年：2015
- 卷：54
- 期：Complete
- 页码：35-46
- 全文大小：2150 K
文摘
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BDNF promotes the growth of embryonic human spinal cord neurons.
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BDNF upregulation resulted in enhancement of BDNF pathway and inhibition of GSK-3β.
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The regulatory effect of BDNF is suppressed by GSK-3β inhibition.