- 作者：Judith L. Meijer ; MSc (Researcher)a ; Claudi L.H. Bockting ; PhD (Professor)b ; Ronald P. Stolk ; MD ; PhD (Professor)a ; Roman Kotov ; PhD (Assistant Professor)c ; Johan Ormel ; PhD (Professor)d ; Huibert Burger ; MD ; PhDe ; h.burger@umcg.nl" class="auth_mail (Associate Professor of Epidemiology)
- 关键词：Pregnancy ; Depression ; Anxiety ; Life change events
- 刊名：Midwifery
- 出版年：May, 2014
- 年：2014
- 卷：30
- 期：5
- 页码：526-531
- 全文大小：268 K
Objective
to investigate the association of life events during pregnancy with change in antenatal anxiety and depression symptoms. We distinguished pregnancy related and non-pregnancy related events and assessed specificity of these associations for depressive or anxious symptoms. In addition, we investigated whether the associations were affected by personality or childhood adversities.Design
observational prospective cohort study
Setting
primary and secondary obstetric care centres in the Netherlands
Participants
1603 women during their first trimester of pregnancy between May 2010 and May 2012
Measurements and findings
we performed linear regression analyses to test the associations of pregnancy related, non-pregnancy related life events, childhood adversities and the personality traits neuroticism and extraversion with the change in symptoms of anxiety (State Trait Anxiety Inventory) and depression (Edinburgh Postnatal Depression Scale) from week 12 to week 36.
Life events during pregnancy were associated with increasing antenatal symptoms of anxiety and depression. Effect sizes associated with the highest numbers of events observed ranged from 0.59 to 1.31. Pregnancy related events were specifically associated with increasing symptoms of anxiety (p=0.009), whereas non-pregnancy related events were merely associated with an increase in symptoms of depression (p<0.001). Neither personality traits nor childhood trauma influenced the associations under study.
Key conclusions
the most important finding is that pregnancy related life events during pregnancy increase levels of antenatal anxiety, whereas depression levels increase when women experience life events that are unrelated to pregnancy. Furthermore, non-pregnancy related events show stronger associations with increases in symptoms of anxiety or depression compared to pregnancy related events.
Implications for practice
our findings may help midwives to tailor psychosocial care to the specific risks of the pregnant woman which may eventually have a positive impact on the health of mother and child.