Characterization of specific antigenic epitopes and the nuclear export signal of the Porcine circovirus 2 ORF3 protein
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- 作者：Jinyan Gua ; 1 ; Lun Wangb ; 1 ; Yulan Jinb ; Cui Linb ; Huijuan Wangb ; Niu Zhoub ; Gang Xinga ; Min Liaob ; liaomin4545@zju.edu.cn" class="auth_mail" title="E-mail the corresponding author ; Jiyong Zhoua ; b ; c ; jyzhou@zju.edu.cn" class="auth_mail" title="E-mail the corresponding author
- 关键词：PCV2 ; ORF3 protein ; NLS ; NES ; Epitope
- 刊名：Veterinary Microbiology
- 出版年：2016
- 出版时间：29 February 2016
- 年：2016
- 卷：184
- 期：Complete
- 页码：40-50
- 全文大小：2085 K
文摘
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We develop a new mAb to ORF3 recognizing natural ORF3 protein in PCV2 infected cell.
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We analyze the linear epitope of ORF3 protein using mAbs to ORF3 protein.
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We analyze the distributions of ORF3 protein in PCV2 infected cells and in ORF3 transfected cells.
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Finally, we identify a nuclear export signal (NES) in ORF3.