AVE 0991 attenuates cardiac hypertrophy through reducing oxidative stress
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- 作者：Yuedong Ma1 ; Huiling Huang1 ; Jingzhou Jiang1 ; Lingling Wu ; Chunxi Lin ; Anli Tang ; Gang Dai ; Jiangui He ; 2 ; hejiangui@163.com" class="auth_mail" title="E-mail the corresponding author ; Yili Chen ; 2 ; 3160992650@qq.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：AVE 0991 ; Cardiac hypertrophy ; Oxidative stress ; Pressure overload
- 刊名：Biochemical and Biophysical Research Communications
- 出版年：2016
- 出版时间：10 June 2016
- 年：2016
- 卷：474
- 期：4
- 页码：621-625
- 全文大小：1104 K
文摘
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Mice model with pressure overload were induced by aortic banding.
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AVE 0991 treatment prevented cardiac hypertrophy and improved cardiac function.
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AVE 0991 might be a new effective therapeutic strategy for cardiac hypertrophy.