Persistent DNMT3A mutation burden in DNMT3A mutated adult cytogenetically normal acute myeloid leukemia patients in long-term remission
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- 作者：Yanjun Suna ; c ; 1 ; Hongjie Shena ; b ; 1 ; Ting Xua ; 1 ; Zhen Yanga ; Huiying Qiua ; b ; Aining Suna ; b ; c ; Suning Chena ; b ; Depei Wu ; MDa ; b ; c ; wudepei@medmail.com.cn" class="auth_mail" title="E-mail the corresponding author ; Yang Xu ; MDa ; b ; c ; xuyang1020@126.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：CN-AML ; DNMT3A mutation ; Burden ; Clonal hematopoiesis
- 刊名：Leukemia Research
- 出版年：2016
- 出版时间：October 2016
- 年：2016
- 卷：49
- 期：Complete
- 页码：102-107
- 全文大小：1010 K
文摘
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DNMT3A mutations burden existed in DNMT3Amut CN-AML patients with long-term remission.
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Next-generation sequencing to explore the potential leukemogenesis mechanism of DNMT3A mutation.
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DNMT3A mutation was an early event in the leukemogenesis.