Medullary Reticular Neurons Mediate Neuropeptide Y-Induced Metabolic Inhibition and Mastication

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• 作者：Yoshiko Nakamura¹ ; Yuchio Yanagawa² ; Shaun F. Morrison³ ; Kazuhiro Nakamura¹ ; ⁴ ; ⁵ ; ^{kazu@med.nagoya-u.ac.jp}
• 关键词：brown adipose tissue ; cardiovascular ; feeding ; hunger ; medulla ; metabolism ; neural circuit ; obesity ; sympathetic ; thermoregulation
• 刊名：Cell Metabolism
• 出版年：2017
• 出版时间：7 February 2017
• 年：2017
• 卷：25
• 期：2
• 页码：322-334
• 全文大小：3343 K
• 卷排序：25

文摘

GABAergic IRt/PCRt neurons innervate sympathetic premotor neurons controlling BAT Selective activation of GABAergic IRt/PCRt neurons inhibits BAT thermogenesis Hypothalamic NPY inhibits BAT thermogenesis by activating GABAergic IRt/PCRt neurons GABAergic IRt/PCRt neurons can also mediate hunger-driven mastication and feeding