In vitro OECD test methods applied to screen the estrogenic effect of chemicals, used in Korea
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- 作者：Hee-Seok Lee1 ; Eun-Jung Park1 ; Songyi Han ; Gyeong-Yong Oh ; Min-Hee Kim ; Hui-Seung Kang ; Jin-Hyang Suh ; Jae-Ho Oh ; Kwang-Soo Lee ; Myung-Sil Hwang ; Guiim Moon ; Jin-Hwan Hong ; In-Gyun Hwang ; hslee0515@gmail.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：Household product ; Human estrogen receptor ; Agonist ; Antagonist ; OECD test guideline
- 刊名：Food and Chemical Toxicology
- 出版年：2016
- 出版时间：September 2016
- 年：2016
- 卷：95
- 期：Complete
- 页码：121-127
- 全文大小：701 K
文摘
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OECD in vitro assays applied for screening of the agonistic/antagonistic effect against human ER on 27 chemicals.
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No chemicals exhibited the agonistic effect against human ER.
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Five surfactants have been found week antagonistic activities mediated by binding affinity against ER.