Transcriptomic evaluation of the American oyster, Crassostrea virginica, deployed during the Deepwater Horizon oil spill: Evidence of an active hydrocarbon response pathway
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- 作者：Matthew J. Jennya ; mjjenny@ua.edu" class="auth_mail" title="E-mail the corresponding author ; William C. Waltonb ; Samantha L. Paytona ; John M. Powersa ; Robert H. Findlaya ; Britton O'Shieldsa ; Kirsten Digginsa ; Mark Pinkertona ; Danielle Portera ; Daniel M. Cranea ; Jeffrey Tapleya ; Charles Cunninghamc
- 关键词：Oyster ; Biomarker ; Transcriptomics ; Aryl hydrocarbon receptor pathway ; Stress response ; Polycyclic aromatic hydrocarbons
- 刊名：Marine Environmental Research
- 出版年：2016
- 出版时间：September 2016
- 年：2016
- 卷：120
- 期：Complete
- 页码：166-181
- 全文大小：3301 K
文摘
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Deployed oysters were used to monitor effects of the 2010 Macondo oil spill.
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Next-generation sequencing was used to identify classic stress response genes.
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Deployed oysters expressed multiple genes associated with hydrocarbon toxicity.
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Expression of multiple genes significantly correlated with PAH tissue levels.