Copper incorporated microporous chitosan-polyethylene glycol hydrogels loaded with naproxen for effective drug release and anti-infection wound dressing

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• 作者：Sandeep K. Mishra ; D. Sujitha Mary ; S. Kannan ; ^{para_kanna@yahoo.com}
• 关键词：Chitosan ; Polyethylene glycol ; Cu2+ ; Antibacterial ; Sustained drug release
• 刊名：International Journal of Biological Macromolecules
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：95
• 期：Complete
• 页码：928-937
• 全文大小：4242 K
• 卷排序：95

文摘

Formation of Copper ion incorporated microporous chitosan-polyethylene glycol films. Mechanically stable films are developed without compromising moisture permeability. Degradation studies revealed stability of films against lysozyme and H2O2. Superiority antibacterial activity and inhibition of biofilm formation. Sustained drug release with excellent keratinocyte cell response.