Human, vector and parasite Hsp90 proteins: A comparative bioinformatics analysis
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- 作者：Ngonidzashe Faya ; David L. Penkler ; Ö ; zlem Tastan Bishop ; O.TastanBishop@ru.ac.za" class="auth_mail" title="E-mail the corresponding author
- 关键词：GRAVY ; grand average of hydropathicity ; Hop ; Hsp70/90 organizing protein ; Hsps ; heat shock proteins ; M domain ; middle domain ; ML ; Maximum Likelihood ; MSA ; multiple sequence analysis ; NJ ; Neighbor Joining
- 刊名：FEBS Open Bio
- 出版年：2015
- 出版时间：2015
- 年：2015
- 卷：5
- 期：Complete
- 页码：916-927
- 全文大小：4903 K
文摘
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Cytosolic Hsp90s are more conserved than those from mitochondrial and ER.
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Cell environment plays a role in the overall physicochemical properties of Hsp90s.
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Serine and tyrosine are favored phosphorylated residues of Hsp90s.
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Mitochondrial and ER Hsp90s have motifs unique to specific organisms.