The pH-specific synthesis, spectroscopic, structural, and magnetic properties of a new Ni(II) species containing the plant physiological binder d

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• 作者：M. Menelaou ; C. Mateescu ; H. Zhao ; N. Lalioti ; A. Salifoglou
• 关键词：Nickel(II)– ; quinate binary interactions ; Aqueous structural speciation ; X-ray structure ; Solid state-solution structure correlation ; Nickel toxicity
• 刊名：Polyhedron
• 出版年：2009
• 出版时间：1 April 2009
• 年：2009
• 卷：28
• 期：5
• 页码：883-890
• 全文大小：665 K

文摘

Nickel is an element present in the abiotic and biological world. In its capacity to promote chemistry at the cellular level, Ni(II) interacts with physiological ligands, thus influencing physiological or pathological conditions. Efforts to comprehend the underlying chemistries led to the investigation of Ni(II) reactivity toward the physiological d-(−)-quinic acid, under pH-specific conditions, facilitating the isolation of a new species Na[Ni(C₇H₁₁O₆)₃] · 2.75H₂O (1). Compound 1 was characterized by elemental analysis, spectroscopic techniques (FT-IR, UV–Visible), magnetic susceptibility studies, and X-ray crystallography. The lattice of 1 reveals the presence of an octahedral Ni(II) complex bound to three quinate ligands through the α-hydroxycarboxylate group, thus projecting a stable entity. Concurrent aqueous speciation studies on the Ni(II)–quinate binary system unravel the nature and properties of species arising from Ni(II)–quinate interactions. To this end, the structural and spectroscopic properties of 1, in the solid state and in solution, are in line with the aqueous speciation, exemplifying key features of Ni(II) interactions with the low molecular mass quinic acid in biologically relevant fluids. The overall physicochemical profile of 1 projects well-defined soluble and potentially bioavailable Ni(II) species that could be involved in specific chemical processes and (bio)chemical reactivity patterns at the physiological or molecular toxicity level.