MiR-30e suppresses proliferation of hepatoma cells via targeting prolyl 4-hydroxylase subunit alpha-1 (P4HA1) mRNA
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- 作者：Guoxing Fenga ; 1 ; Hui Shib ; 1 ; Jiong Lia ; Zhe Yanga ; Runping Fangb ; Lihong Yeb ; Weiying Zhanga ; zhwybao@nankai.edu.cn" class="auth_mail" title="E-mail the corresponding author ; Xiaodong Zhanga ; zhangxd@nankai.edu.cn" class="auth_mail" title="E-mail the corresponding author
- 关键词：MiR-30e ; P4HA1 ; Proliferation ; Hepatocellular carcinoma
- 刊名：Biochemical and Biophysical Research Communications
- 出版年：2016
- 出版时间：8 April 2016
- 年：2016
- 卷：472
- 期：3
- 页码：516-522
- 全文大小：1016 K
文摘
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P4HA1 is a novel target gene of miR-30e.
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P4HA1 is increased in clinical HCC tissues.
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MiR-30e is negatively correlated with P4HA1 in clinical HCC tissues.
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MiR-30e suppresses the proliferation of HCC cells through targeting P4HA1 mRNA.