Levosimendan beyond inotropy and acute heart failure: Evidence of pleiotropic effects on the heart and other organs: An expert panel position paper
详细信息 查看全文
- 作者：Dimitrios Farmakisa ; dimitrios_farmakis@yahoo.com" class="auth_mail" title="E-mail the corresponding author ; Julian Alvarezb ; Tuvia Ben Galc ; Dulce Britod ; Francesco Fedelee ; Candida Fonsecaf ; Anthony C. Gordong ; Israel Gotsmanh ; Elena Grossinii ; Fabio Guarracinoj ; Veli-Pekka Harjolak ; Yaron Hellmanl ; Leo Heunksm ; Visnja Ivancann ; Apostolos Karavidaso ; Matti Kivikkop ; Vladimir Lomivorotovq ; Dan Longroisr ; Josep Masips ; Marco Metrat ; Andrea Morelliu ; Maria Nikolaouv ; Zoltá ; n Pappw ; Alexander Parkhomenkox ; Gerhard Poelzly ; Piero Pollesellop ; Hanne Berg Ravnz ; Steffen Rexaa ; Hynek Rihaab ; Sven-Erik Rickstenac ; Robert H.G. Schwingerad ; Bojan Vrtovecae ; M. Birhan Yilmazaf ; Marzenna Zielinskaag ; John Parissisa
- 关键词：Levosimendan ; Inotropes ; Heart failure ; Cardiogenic shock ; Cardioprotection ; Organ protection
- 刊名：International Journal of Cardiology
- 出版年：2016
- 出版时间：1 November 2016
- 年：2016
- 卷：222
- 期：Complete
- 页码：303-312
- 全文大小：991 K
文摘
- •
Levosimendan is a positive inotrope with vasodilating properties.
- •
It is indicated for decompensated heart failure with low cardiac output.
- •
Levosimendan bears pleiotropic effects beyond inotropy including organoprotection.
- •
Therefore, it may be beneficial in conditions beyond decompensated heart failure.
- •
Further trials are needed to explore potential translation into clinical practice.