From Pavlov to pain: How predictability affects the anticipation and processing of visceral pain in a fear conditioning paradigm
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- 作者：Franziska Labrenza ; Adriane Icenhoura ; Marc Schlamannb ; c ; Michael Forstingb ; Ulrike Bingeld ; Sigrid Elsenbrucha ; sigrid.elsenbruch@uk-essen.de" class="auth_mail" title="E-mail the corresponding author
- 关键词：Visceral pain ; Fear conditioning ; Associative learning ; Anticipation ; Expectation ; Predictability
- 刊名：NeuroImage
- 出版年：2016
- 出版时间：15 April 2016
- 年：2016
- 卷：130
- 期：Complete
- 页码：104-114
- 全文大小：1416 K
文摘
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We addressed the impact of fear on visceral hyperalgesia and central sensitization.
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Pain-related fear was assessed through two groups of different predictability.
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Pain predictability affected neural pain processes and altered associative learning.
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During aversive learning, unpredictability amplified pain encoding, and modulation.
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Pain-related fear does not promote visceral hyperalgesia or central sensitization.