Neonatal serotonin reuptake inhibition reduces hypercaloric diet effects on fat mass and hypothalamic gene expression in adult rats
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- 作者：Lí ; gia Cristina Monteiro Galindoa ; galindo.ligia1@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Manuella da Luz Duarte Barrosd ; manuella.daluz@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Isabeli Lins Pinheiroc ; isabeli.lins@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Ricardo Vinicius de Carvalho Santanaa ; rvcs.fisioterapia@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Rhowena Jane Barbosa de Matosc ; rhowenajane@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Carol Gó ; is Leandroc ; carolleandro22@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Sandra Lopes de Souzaa ; sanlopesufpe@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Raul Manhã ; es de Castrob ; manhaesdecastroraul@gmail.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：Developmental plasticity ; Serotonin ; SSRI ; Rats ; Food intake ; Hypercaloric diet ; Adipose tissue
- 刊名：International Journal of Developmental Neuroscience
- 出版年：2015
- 出版时间：November 2015
- 年：2015
- 卷：46
- 期：Complete
- 页码：76-81
- 全文大小：923 K
文摘
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Early SSRI-treated rats showed lower food intake and less NPY and 5-HT2C hypothalamic in adulthood
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SSRI-treated rats showed increased 5-HT2C and decreased NPY expression after hypercaloric diet.
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SSRI-treated rats had less fat pad mass after hypercaloric diet.