Global gene expression changes in the prefrontal cortex of rabbits with hypercholesterolemia and/or hypertension

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• 作者：Sau-Yeen Loke^a ; Peter Tsun-Hon Wong^b ; Wei-Yi Ong^a ; ^c ; ^{wei_yi_ong@nuhs.edu.sg}
• 关键词：Cholesterol ; Hypertension ; Proteasome ; Insulin ; Histone ; Inflammation
• 刊名：Neurochemistry International
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：102
• 期：Complete
• 页码：33-56
• 全文大小：5395 K
• 卷排序：102

文摘

The prefrontal cortices of hypercholesterolemic rabbits were analyzed by microarray. Networks include proteasome, histone, insulin and cell signaling pathways. Increased amyloid beta peptide was found on cortical neurons.