Brain hyperintensity location determines outcome in the triad of impaired cognition, physical health and depressive symptoms: A cohort study in late life
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- 作者：Alison Murraya ; a.d.murray@abdn.ac.uk" class="auth_mail" title="E-mail the corresponding author ; Chris McNeila ; c.mcneil@abdn.ac.uk" class="auth_mail" title="E-mail the corresponding author ; Sima Salarirada ; s.salari@abdn.ac.uk" class="auth_mail" title="E-mail the corresponding author ; Ian Dearyb ; iand@staffmail.ed.ac.uk" class="auth_mail" title="E-mail the corresponding author ; Louise Phillipsa ; louise.phillips@abdn.ac.uk" class="auth_mail" title="E-mail the corresponding author ; Lawrence Whalleya ; l.j.whalley@abdn.ac.uk" class="auth_mail" title="E-mail the corresponding author ; Roger Staffc ; r.staff@abdn.ac.uk" class="auth_mail" title="E-mail the corresponding author
- 关键词：WMH ; white matter hyperintensities ; PVH ; periventricular hyperintensities ; ABC36 ; Aberdeen 1936 Birth Cohort ; GMH ; grey matter hyperintensities ; ITH ; infratentorial hyperintensities ; SEM ; structural equation model ; PCA ; principle components analysis
- 刊名：Archives of Gerontology and Geriatrics
- 出版年：2016
- 出版时间：March-April 2016
- 年：2016
- 卷：63
- 期：Complete
- 页码：49-54
- 全文大小：589 K
文摘
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Illustrates how location of brain hyperintensities influences depressive outcomes.
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Illustrates the use of structural equation modelling with highly correlated variables.
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Unpicks relationships between brain hyperintensities and components of frailty.