Hypersensitivity Reactions to Corticosteroids
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- 作者：L. Berbegal ; lauraberbegal@gmail.com" class="auth_mail" title="E-mail the corresponding author ; F.J. DeLeon ; J.F. Silvestre
- 关键词：Allergic contact dermatitis ; Hypersensitivity reactions ; Patch test ; Standard battery ; Corticosteroids
- 刊名：Actas Dermo-Sifiliográficas (English Edition)
- 出版年：2016
- 出版时间：March 2016
- 年：2016
- 卷：107
- 期：2
- 页码：107-115
- 全文大小：1644 K
文摘
Corticosteroids are widely used in clinical practice. In dermatology, their application is generally topical. These substances may act as allergens and produce immediate and delayed hypersensitivity reactions. Allergic contact dermatitis is the most frequent presentation of corticosteroid allergy and it should be studied by patch testing in specific units. The corticosteroids included in the Spanish standard battery are good markers but not ideal. Therefore, if those makers are positive, it is useful to apply a specific battery of corticosteroids and the drugs provided by patients. Immediate reactions are relatively rare but potentially severe, and it is important to confirm the sensitization profile and to guide the use of alternative corticosteroids, because they are often necessary in several diseases. In this article we review the main concepts regarding these two types of hypersensitivity reactions in corticosteroid allergy, as well as their approach in the clinical practice.