Proposal of a magnetohyperthermia system: preliminary biological tests
详细信息 查看全文
- 作者：Guedes ; M.H.A. ; Guedes ; M.E.A. ; Morais ; P.C. ; Da Silva ; M.F. ; Santos ; T.S. ; Alves Jr ; J.P. ; Bertelli ; C.E. ; et. al.
- 关键词：87.50.&minus ; a ; 87.50.Mn ; Alternating magnetic field ; Magnetothermocytolysis ; Genotoxicity ; Hyperthermia ; Inflammation
- 刊名：Journal of Magnetism and Magnetic Materials
- 出版年：2004
- 出版时间：May, 2004
- 年：2004
- 卷：272-276
- 期：Part 3
- 页码：2406-2407
- 全文大小：156 K
文摘
Magnetohyperthermia (MHT) has been proposed as an alternative therapy for cancer treatment. In order to perform MHT tests we have developed an apparatus operating at 1MHz with AC magnetic field of 40Oe in amplitude. Biological tests were performed after exposing the peritoneum region of mice to the AC field. Significative alterations were observed only when peritoneum was exposed by 10min. The data allowed to conclude that: (1) the damage induced by the AC field to normal cells is related to the exposure time and (2) the equipment developed is adequate to perform MHT experiments.