Hypocrellin B and paclitaxel-encapsulated hyaluronic acid-ceramide nanoparticles for targeted photodynamic therapy in lung cancer
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- 作者：Ji-Eun Changa ; Hyun-Jong Choc ; Eunjue Yia ; Dae-Duk Kimd ; Sanghoon Jheona ; b ; jheon@snu.ac.kr" class="auth_mail" title="E-mail the corresponding author
- 关键词：Photodynamic therapy ; Hypocrellin B ; Paclitaxel ; Hyaluronic acid&ndash ; ceramide nanoparticle ; Lung cancer
- 刊名：Journal of Photochemistry and Photobiology B: Biology
- 出版年：2016
- 出版时间：May 2016
- 年：2016
- 卷：158
- 期：Complete
- 页码：113-121
- 全文大小：2667 K
文摘
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Hyaluronic acid–ceramide nanoparticles were prepared for lung cancer targeted PDT.
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Combination therapy of chemotherapy and PDT was performed against lung cancer.
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In vitro and in vivo antitumor efficacies were enhanced by prepared nanoparticles.
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Developed nanoparticles were suggested as a potential drug delivery system in PDT