Changes in the female arcuate nucleus morphology and neurochemistry after chronic ethanol consumption and long-term withdrawal
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- 作者：Elce C.C. Rebouç ; asa ; b ; c ; elcecristina@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Sandra Lealb ; c ; d ; sleal@med.up.pt" class="auth_mail" title="E-mail the corresponding author ; Susana M. Silvab ; c ; ssilva@med.up.pt" class="auth_mail" title="E-mail the corresponding author ; Susana I. Sá ; b ; c ; sasusana@med.up.pt" class="auth_mail" title="E-mail the corresponding author
- 关键词：Hypothalamic arcuate nucleus ; Heavy chronic ethanol treatment ; Long-term withdrawal ; Feeding-regulatory neuropeptides ; Estrogen receptor ; Tyrosine hydroxylase
- 刊名：Journal of Chemical Neuroanatomy
- 出版年：2016
- 出版时间：November 2016
- 年：2016
- 卷：77
- 期：Complete
- 页码：30-40
- 全文大小：3529 K
文摘
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Eight months of 20% ethanol intake induced no structural damage in the female ARN.
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Two months withdrawal induced volume and neuronal loss in the female ARN.
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Chronic ethanol intake nor its withdrawal affects α-MSH or TH expression in the female ARN.
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Two months withdrawal increased the number of neurons expressing NPY in the ARN.