Early-life adversity and brain development: Is the microbiome a missing piece of the puzzle?

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• 作者：S.M. O&rsquo ; Mahony^a ; ^b ; ^{somahony@ucc.ie} ; G. Clarke^b ; ^c ; T.G. Dinan^b ; ^c ; J.F. Cryan^a ; ^b ; ^{j.cryan@ucc.ie}
• 关键词：ASD ; autism spectrum disorder ; BMI ; body mass index ; HPA ; hypothalamic&ndash ; pituitary&ndash ; adrenal ; IBD ; inflammatory bowel disease ; IBS ; irritable bowel syndrome
• 刊名：Neuroscience
• 出版年：2017
• 出版时间：7 February 2017
• 年：2017
• 卷：342
• 期：Complete
• 页码：37-54
• 全文大小：1002 K
• 卷排序：342

文摘

Vulnerable neurodevelopmental windows exist during the life span. Adverse events during these times include altered gut microbiota. Increased knowledge about parallel colonization events and brain development is required. This is essential from a preventative, diagnostic and therapeutic perspective.