LRRTM3 Regulates Excitatory Synapse Development through Alternative Splicing and Neurexin Binding
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- 作者：Ji Won Um1 ; 2 ; 8 ; Tae-Yong Choi3 ; 8 ; Hyeyeon Kang2 ; Yi Sul Cho4 ; Gayoung Choii1 ; Pavel Uvarov5 ; Dongseok Park2 ; Daun Jeong6 ; Sangmin Jeon1 ; Dongmin Lee7 ; Hyun Kim7 ; Seung-Hee Lee6 ; Yong-Chul Bae4 ; Se-Young Choi3 ; Matti S. Airaksinen5 ; Jaewon Ko1 ; jaewonko@yonsei.ac.kr" class="auth_mail" title="E-mail the corresponding author
- 关键词：LRRTM3 ; LRRTM4 ; neurexin ; glypican ; excitatory synapse development ; alternative splicing ; dentate gyrus
- 刊名：Cell Reports
- 出版年：2016
- 出版时间：2 February 2016
- 年：2016
- 卷：14
- 期：4
- 页码：808-822
- 全文大小：7000 K
文摘
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Alternative splicing of Lrrtm3 and Lrrtm4 mRNAs produces distinct protein variants
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LRRTM3 is required for DG excitatory synapse development in vitro and in vivo
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LRRTM3 regulates activity-dependent AMPAR surface expression
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Neurexins are universal ligands for all LRRTMs