Self-assembly of biogenic gold nanoparticles and their use to enhance drug delivery into cells
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- 作者：Ji Min Seo1 ; Eun Bee Kim1 ; Moon Seop Hyun ; Bo Bae Kim ; Tae Jung Park ; tjpark@cau.ac.kr" class="auth_mail" title="E-mail the corresponding author
- 关键词：Biosynthesis ; Heavy metal binding proteins ; Gold nanoparticles ; Drug delivery system ; Cytotoxicity
- 刊名：Colloids and Surfaces B: Biointerfaces
- 出版年：2015
- 出版时间：1 November 2015
- 年：2015
- 卷：135
- 期：Complete
- 页码：27-34
- 全文大小：3541 K
文摘
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Recombinant heavy-metal binding protein (HMBP) to synthesize biogenic gold nanoparticles (AuNPs).
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AuNPs bound with HMBPs through interactions with specific amino acid sequence.
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Simple, rapid, effective drug delivery system of use.
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Biocompatible carrier than chemically synthesized materials.
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Efficient anti-cancer agent with high cytotoxicity for cancer chemotherapy.