Au(I)-catalyzed tandem [3,3]-sigmatropic rearrangement–cycloisomerization cascade as a route to spirocyclic furans

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• 作者：Hyun-Suk Yeom ; Suk-Jae Yoon ; Seunghoon Shin
• 刊名：Tetrahedron Letters
• 出版年：2007
• 出版时间：9 July 2007
• 年：2007
• 卷：48
• 期：28
• 页码：4817-4820
• 全文大小：137 K

文摘

Gold-catalyzed reaction of 1-(3-hydroxypropynyl)cycloalkanol derivatives was studied. The reaction profile was highly dependent on the ring size, migrating group, as well as reaction conditions. An efficient route to spirocyclic furans via tandem [3,3]-sigmatropic rearrangement–cycloisomerization is reported.