A systematic review of the psychobiological burden of informal caregiving for patients with dementia: Focus on cognitive and biological markers of chronic stress

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• 作者：Andrew P. Allen^a ; ^b ; Eileen A. Curran^c ; ^d ; Á ; ine Duggan^e ; John F. Cryan^a ; ^f ; Aoife N&iacute ; Chorcorá ; in^g ; Timothy G. Dinan^a ; ^b ; D. William Molloy^g ; Patricia M. Kearney^c ; ^d ; Gerard Clarke^a ; ^b ; ^{G.Clarke@ucc.ie}
• 关键词：Stress ; Caregiver ; Dementia ; Cortisol ; Immune system ; Cardiovascular ; Epinephrine ; Norepinephrine ; Cognition ; Attention ; Memory ; Biomarker
• 刊名：Neuroscience & Biobehavioral Reviews
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：73
• 期：Complete
• 页码：123-164
• 全文大小：2075 K
• 卷排序：73

文摘

Much research has examined biomarkers of chronic stress in dementia caregivers. Cortisol was increased in dementia caregivers in most studies examining cortisol. Dementia caregivers displayed poorer attention and executive function performance. Interventions to reduce stress in caregivers may improve cognition. Risk of bias was generally low to moderate.