In vivo relevant mixed urolithins and ellagic acid inhibit phenotypic and molecular colon cancer stem cell features: A new potentiality for ellagitannin metabolites against cancer
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文摘
<p id="p0010">Microbiota phenolic-derived metabolites can battle colon cancer stem cells (CSCs).p>
<p id="p0015">Urolithins (Uros) and ellagic acid (EA) inhibit CSC features in vitro and ex vivo.p>
<p id="p0020">Mixed Uros and EA inhibit the formation and growth of colonospheres.p>
<p id="p0025">Mixed Uros and EA reduce ALDH-expressing cell population of CSCs.p>
<p id="p0030">Potential effect of Uros on the recurrence and chemoresistance of colon cancer.p>

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